Authors

FARIBA KHANIPOUYANI1,*, FATEME ABBASALIZADE2, SHAMSI ABBASALIZADE2, ZAHRA FARDIAZAR2, SHAMSI GHAFFARI3, PARVIN SARBAKHSHI4

Departments

1 Department of Obstetrics and Gynecology, School of medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran - 2 Department of Obstetrics and Gynecology, Tabriz University of Medical Sciences, School of Medicine, Tabriz, Iran - 3 Department of Pediatrics, School of medicine, Tabriz University of Medical Sciences, Tabriz, Iran - 4 Department of Statistics and Epidemiology, School of Public Health, Tabriz Medical University of Medical Sciences, Tabriz, Iran

Abstract

Aim: To determine whether main pulmonary artery Doppler indices correlate with fetal lung maturity.

Materials and methods: This prospective cohort study was designed to study Doppler Indices (Plasticity Index, Resistance Index, Systolic- to- Diastolic ratio, Peak systolic Velocity, Acceleration time & Ejection time) in MPA of fetuses in women which impend preterm birth in 3rd trimester (28-37 wks)

Results: 23 of 145 fetuses (15.86%) developed RDS.Et, at & At/Et ratio of their MPA Doppler were positively correlated with gestational age. S/D ratio, PSV, RI and PI didn`t show correlation with fetal lung maturity.At/Et ratio had strongest predictive value for fetal lung maturity. At/Et ratio cut point ≥0.304 predicted fetal lung maturity in fetuses of 28-37 wks gestational age(sensitivity=94.3%,specificity=95.7%,positive predictive value=99.1% and negative predictive value =75,9%).

Conclusion: Fetal MPA Doppler At/Et ratio can predicts FLM with high sensitivity and specificity as a noninvasive test.

Keywords

pulmonary artery Doppler, fetal lung maturity.