Aim: Platelet to lymphocyte ratio (PLR) was revaled to have a close relation with major adverse cardiovascular outcomes. The aim of this study was to investigate the association between PLR and lesion localization of left anterior descending artery (LAD) in ST-segment elevation myocardial infarction (STEMI) patients.
Materials and methods: Patients admitted to our hospital with acute anterior STEMI were included. 58 patients who have sin- gle-vessel disease at LAD and their hematological parameters were analyzed retrospectively. Proximal segment of LAD lesions were groupped as Group I and mid segment of the LAD lesion groupped as Group II. The groups were compared according to their PLR and other parameters.
Results: Between group I (n = 41, mean age 52.5 ± 12.7) and group II (n = 17, mean ages 52.0 ± 10.8); PLR, was significantly higher in group I (159 ± 99 vs 99.5 ± 37.5 p < 0.05). In group I, left ventricular ejection fraction (LVEF) was significantly lower (P = 0.02). In correlation analyzes, PLR was positively correlated with Troponin I (r = 0.30, P = 0.03) and negatively correlated with LVEF (r= - 0.27 , P = 0.04)
Conclusion: The present study demonstrated that anterior STEMI patients with high PLR had a greater possibility having proximal culprit lesion on the LAD. Therefore PLR can be used as a useful tool to detect not only significant atherosclerosis but also culprit plaque localization in patients with acute STEMI patients.
Coronary artery disease, platelet to lymphocyte ratio, acute coronary syndrome