Introduction: Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by attacks of fever and serositis. Patients with FMF may use a lot of medications associated with the clinical symptoms. Drugs that are used in the treatment of FMF may cause bone loss. The aim of this study was to define mandibular bone mineral density (BMD) in adults with FMF using dual energy X-ray absorptiometry (DXA) technique.
Materials and methods: The study comprised 28 patients diagnosed with FMF (male/female: 16/12), and 32 healthy control subjects (male/female: 18/14) with no history of inflammatory disease. The BMD of each mandible was measured by DXA.
Results: There was no statistically significant difference in gender, age or body mass index (BMI) between the FMF patients and the control group but mandibular BMD was significantly decreased in patients with FMF.
Conclusion: However, it is di cult to draw any conclusions from the current cross-sectional study, FMF were found to be associated with decreased mandibular bone density.The results of the present study revealed that the mandibular BMD level was lower in FMF patients than in the control group.
Familial mediterranean fever, bone density, mandible, dual energy X-ray absorptiometry